2-CHLORO-3-FLUOROPYRIDINE-5-BORONIC ACID

2-CHLORO-3-FLUOROPYRIDINE-5-BORONIC ACID - Names and Identifiers

Name	Boronicacid, B-(6-chloro-5-fluoro-3-pyridinyl)-
Synonyms	(6-Chloro-5-fluoropyridin-3-yl) 2-CHLORO-3-FLUOROPYRIDINE-5-BORONIC ACID 2-Chloro-3-fluoropyridine-5-boronic acid 6-Chloro-5-fluoropyridine-3-boronic acid (6-CHLORO-5-FLUOROPYRIDIN-3-YL)BORONIC ACID 6-chloro-5-fluoropyridin-3-yl-3-boronic acid B-(6-Chloro-5-fluoro-3-pyridinyl)boronic acid 6-chloro-5-fluoropyridin-3-yl-3-ylboronic acid Boronicacid, B-(6-chloro-5-fluoro-3-pyridinyl)- Boronic acid, B-(6-chloro-5-fluoro-3-pyridinyl)-
CAS	1072946-66-7

2-CHLORO-3-FLUOROPYRIDINE-5-BORONIC ACID - Physico-chemical Properties

Molecular Formula	C5H4BClFNO2
Molar Mass	175.35
Density	1.51
Boling Point	325.4±52.0 °C(Predicted)
pKa	5.65±0.11(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C

2-CHLORO-3-FLUOROPYRIDINE-5-BORONIC ACID - Introduction

2-Chloro-3-fluoropyridine-5-boronic acid is an organic compound with the chemical formula C5H3BClF2NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2-Chloro-3-fluoropyridine-5-boronic acid is a white crystalline powder.
-Solubility: It is soluble in water and stable under acidic conditions.
-Melting point: about 146-149°C.
-It is a weak acid and can be used as a fluorinating reagent.

Use:
-2-Chloro-3-fluoropyridine-5-boronic acid is widely used in the fluorination reaction of organic synthesis. It can be used as a reagent for introducing fluorine atoms and plays an important role in the fields of medicine, pesticide and chemistry.
-It can also be used for boronation reactions in organic synthesis, as a boron source to participate in the reaction.

Preparation Method:
-A common preparation method is to obtain 2-chloro-3-fluoropyridine -5-boronic acid through the reaction of 2-chloro-5-fluoropyridine and boric acid. The specific operating conditions can be optimized according to actual needs.

Safety Information:
-2-Chloro-3-fluoropyridine-5-boronic acid is a relatively safe compound under general conditions of use. However, as chemical reagents, personal protective measures should be taken when handling, such as wearing laboratory gloves, goggles and laboratory coats. Avoid inhalation, swallowing or contact with skin. Care should be taken to comply with laboratory safety regulations and appropriate waste disposal during use. In case of any accident or discomfort, seek medical attention immediately.

Last Update：2024-04-09 20:45:29